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In addition to our activities in research and education of students in medicine and natural sciences we offer professional consultant services pertaining to drug therapy. Skeletal muscle disease, and neurological disorders. Individual patients creates the opportunity to devise novel pharmacological, gene-based, and cell-based approaches for individualized treatments in patients with heart failure, Simulate disease processes and develop novel therapeutics for organ protection and regeneration is ongoing at the Institute of Pharmacology and Toxicology.

Additional development of different organ surrogates to Tissue engineering enables us to build three-dimensional culture systems with organotypic structure and function. The Institute of Pharmacology and Toxicology employs state-of-the-art conceptsДЇrom pharmacology and biomedical engineering to establish proof-of-concept and translate individualized tissue engineered heart repair. These patients may benefit from reconstruction of functional myocardium using stem cell-based tissue engineering. The majority of patients with heart failure present severe structural and functional cardiac impairments with limited responsiveness to classical pharmacological treatment.

A key challenge is to define primary and secondary processes in heart failure pathology for optimal design of therapeutic strategies. Inputs from developmental biology and aging processes are exploited to identify novel drug targets in cardiomyocytes, non-myocytes, and the extracellular stroma to protect and We employ systems-focused approaches to decipher the complex cellular processes underlying heart failure development with the aim of defining novel therapeutic strategies.